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PRF at a Glance

How is PRF made?
When is PRF used?
Tooth extraction
Sinus Lift
Socket Preservation
Dental Implants

Platelet Rich Fibrin and its use in Dental Treatments

When someone is prescribed an Oral surgical treatment by a dentist, such as wisdom tooth removal, implant treatment or bone regeneration, it is normal to be concerned and worried with a number of factors, including the risks associated to the procedure, recovery time, potential to develop pain or infection following the treatment.


Advances in dental treatments techniques and innovative equipment is changing the perception of dental treatments in general, leading to better outcomes and an overall better experience while at the dentist. One such advancement is the use of PRF (Platelet Rich Fibrin).


PRF is a living biomaterial derived from a patient’s own blood that helps to promote healing and the regeneration of bone and soft tissue, both of which are critical to the success of any oral surgery procedure.

How is PRF made?

The PRF is obtained by collecting a blood sample from the patients arm immediately prior to the dental treatment intervention and placing it into a centrifuge that separates the collected blood into three layers:


1) Clear liquid also called plasma layer

2) Red layer rich in red blood cells

3) Yellow thick layer: the PRF portion


The thick PRF layer is rich in growth factors, platelets, fibrin and circulating stem cells. In addition, the fibrin network is composed of leukocytes and cytokines. All of these play a significant role in inflammation regulation and fighting infection.

When is PRF used?

PRF can be beneficial in a wide variety of dental and oral surgery procedures ranging from wisdom tooth removal, tooth extractions, implant treatments socket preservation and sinus lift procedures.

  • Tooth extraction – Patients’ jawbones have very little blood supply compared to other tissues in the human body, which means this area has less ability to heal and less defense against infection. Placing RFP in the extraction site protects it from infection and delivers proteins that accelerate the healing process.
  • Sinus Lift – This procedure is used when a patient needs an implant in the upper jaw but has a thin sinus wall unable to support implants on its own. A sinus lift is carried out to allow bone growth in the floor of the maxillary sinus to enable the secure placement of dental implants. In this instance, PRF can be used to produce faster, stronger bone and soft tissue healing.
  • Socket Preservation – The primary purpose of socket preservation is to preserve the health of the alveolar bone (i.e. the socket that holds the tooth in place). This bone is often damaged by disease and/or infection, which determine the tooth removal. Once the failing tooth is removed it can create a jaw deformity if preventative measures aren’t taken. In a socket preservation procedure, PRF membranes, which contains bone growth enhancing elements, can be stitched over the wound or a graft material/scaffold that is placed in the socket of an extracted tooth before it is closed.
  • Dental Implants – Insufficient jawbone is one of the leading causes of dental implant failure. In sites where implants are placed, PRF occupies the space between the extraction site and the dental implant, helping to expedite healing and creating jawbone structure.


Benefits of Using Platelet Rich Fibrin

Surgeons and patients alike are benefiting from the increased use of PRF in dental surgical procedures. From decreasing pain to providing a cost-effective option, PRF offers a number of advantages.


  • It’s 100% natural and easy to produce. Because PRF is derived from the patients’ own blood it is 100% natural and readily available. The use of PRF does not require anticoagulants, bovine thrombin, or any other jellying factor. This also means patients have virtually no risk of experiencing a rejection reaction (i.e., a foreign body response), which can potentially happen when synthetic alternatives are used.
  • Significant decrease in patient discomfort. The use of PRF has been shown to reduce the risk of complications and restrictions a patient may experience due to donor site morbidity. The result is a decrease in patient discomfort, post-surgical pain, and post-op bleeding.
  • Faster healing. PRF has been shown to result in faster healing due to its slow polymerization (i.e., the rate at which molecules combine). This process generates a fibrin network that leads to more efficient cell migration and faster healing.
  • High cost-benefit ratio. By reducing the risk of donor site morbidity, the use of PRF can potentially spare the patient from undergoing a second surgery. Due to the fact that PRF is readily available, it is an option for patients to consider.

More About

As noted, dentistry has seen a number of advances in recent years and patients should always consult with their dental provider to discuss which procedures make the most sense based on their individual health history.

Call us at 020 3583 9809 or visit our website at to book your initial consultation and find out whether this is the right treatment for you.

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