How Is PRF Made?
How it works
The PRF is obtained by collecting a blood sample from the patient’s arm immediately before the dental treatment intervention and placing it into a centrifuge that separates the collected blood into three layers:
- 1) Clear liquid, also called plasma layer
- 2) Red layer rich in red blood cells
- 3) Yellow thick layer: the PRF portion
The thick PRF layer is rich in growth factors, platelets, fibrin and circulating stem cells. In addition, the fibrin network is composed of leukocytes and cytokines. All of these play a significant role in inflammation regulation and fighting infection.
Benefits Of Using Platelet Rich Fibrin
Surgeons and patients benefit from the increased use of PRF in dental surgical procedures. From decreasing pain to providing a cost-effective option, PRF offers several advantages.
- It’s 100% natural and easy to produce. Because PRF is derived from the patient’s own blood, it is 100% natural and readily available. PRF does not require anticoagulants, bovine thrombin, or any other jellying factor. This also means patients have virtually no risk of experiencing a rejection reaction (i.e., a foreign body response), which can potentially happen when synthetic alternatives are used.
- Significant decrease in patient discomfort. PRF has been shown to reduce the risk of complications and restrictions a patient may experience due to donor site morbidity. The result is decreased patient discomfort, post-surgical pain, and post-op bleeding.
- Faster healing. PRF has resulted in faster healing due to its slow polymerization (i.e., the rate at which molecules combine). This process generates a fibrin network, leading to more efficient cell migration and faster healing.
- High cost-benefit ratio. By reducing the risk of donor site morbidity, PRF can potentially spare the patient from undergoing a second surgery. Since PRF is readily available, it is an option for patients to consider.
